/* ================================================================
   ORF Verifier Pro — 商务科技风格
   设计理念：专业、务实、可信赖的生物信息学工作站
   ================================================================ */

/* ----- 基础重置 ----- */
*,
*::before,
*::after {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

/* ----- 设计令牌 ----- */
:root {
    /* 主色调 — 专业蓝 */
    --color-primary: #2563eb;
    --color-primary-hover: #1d4ed8;
    --color-primary-light: #eff6ff;
    --color-primary-border: #bfdbfe;

    /* 语义色 */
    --color-success: #059669;
    --color-success-bg: #ecfdf5;
    --color-warning: #d97706;
    --color-warning-bg: #fffbeb;
    --color-error: #dc2626;
    --color-error-bg: #fef2f2;

    /* 中性色 */
    --color-bg: #f1f5f9;
    --color-surface: #ffffff;
    --color-surface-hover: #f8fafc;
    --color-border: #e2e8f0;
    --color-border-light: #f1f5f9;

    /* 文字 */
    --text-primary: #0f172a;
    --text-secondary: #475569;
    --text-tertiary: #94a3b8;
    --text-inverse: #ffffff;

    /* 阴影 */
    --shadow-sm: 0 1px 2px rgba(0, 0, 0, 0.05);
    --shadow-md: 0 4px 12px rgba(0, 0, 0, 0.06), 0 1px 3px rgba(0, 0, 0, 0.04);
    --shadow-lg: 0 12px 32px rgba(0, 0, 0, 0.08), 0 2px 6px rgba(0, 0, 0, 0.04);

    /* 圆角 */
    --radius-sm: 6px;
    --radius-md: 10px;
    --radius-lg: 14px;

    /* 间距 */
    --space-xs: 4px;
    --space-sm: 8px;
    --space-md: 16px;
    --space-lg: 24px;
    --space-xl: 32px;

    /* 字体 */
    --font-sans: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', system-ui, sans-serif;
    --font-mono: 'JetBrains Mono', 'Fira Code', 'Cascadia Code', 'Consolas', monospace;
}

/* ----- 全局 ----- */
html {
    font-size: 15px;
    -webkit-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
}

body {
    font-family: var(--font-sans);
    background: var(--color-bg);
    color: var(--text-primary);
    min-height: 100vh;
    display: flex;
    flex-direction: column;
    line-height: 1.6;
}

/* ----- 导航栏 ----- */
.navbar {
    background: var(--color-surface);
    border-bottom: 1px solid var(--color-border);
    padding: 0 var(--space-lg);
    height: 56px;
    display: flex;
    align-items: center;
    justify-content: space-between;
    position: sticky;
    top: 0;
    z-index: 100;
    box-shadow: var(--shadow-sm);
}

.navbar .logo {
    font-size: 1.05rem;
    font-weight: 700;
    display: flex;
    align-items: center;
    gap: 10px;
    color: var(--text-primary);
    letter-spacing: -0.3px;
    user-select: none;
}

.navbar .logo .dna-icon {
    font-size: 1.5rem;
    display: flex;
    align-items: center;
}

.navbar .menu {
    display: flex;
    gap: 4px;
}

.navbar .menu a {
    color: var(--text-secondary);
    text-decoration: none;
    font-size: 0.85rem;
    font-weight: 500;
    padding: 6px 14px;
    border-radius: var(--radius-sm);
    transition: all 0.15s;
}

.navbar .menu a:hover {
    color: var(--color-primary);
    background: var(--color-primary-light);
}

.db-status {
    display: flex;
    align-items: center;
    gap: 8px;
    font-size: 0.8rem;
    color: var(--text-secondary);
    font-weight: 500;
}

.db-dot {
    width: 8px;
    height: 8px;
    border-radius: 50%;
    background: var(--color-success);
    box-shadow: 0 0 0 3px var(--color-success-bg);
}

/* ----- 主布局 ----- */
.container {
    max-width: 1400px;
    margin: 0 auto;
    padding: var(--space-lg);
    display: flex;
    gap: var(--space-lg);
    flex: 1;
}

.main-panel {
    flex: 1;
    min-width: 0;
}

.side-panel {
    width: 380px;
    min-width: 380px;
    flex-shrink: 0;
}

@media (max-width: 900px) {
    .container {
        flex-direction: column;
    }
    .side-panel {
        width: 100%;
        min-width: unset;
    }
}

/* ----- 卡片 ----- */
.card {
    background: var(--color-surface);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-lg);
    padding: 20px 24px;
    margin-bottom: var(--space-md);
    box-shadow: var(--shadow-sm);
}

.card-title {
    font-weight: 650;
    font-size: 0.95rem;
    margin-bottom: 14px;
    color: var(--text-primary);
    display: flex;
    align-items: center;
    gap: 8px;
    letter-spacing: -0.2px;
}

/* ----- 输入区 ----- */
textarea,
input[type='text'] {
    font-family: var(--font-mono);
    background: var(--color-bg);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-md);
    padding: 10px 14px;
    color: var(--text-primary);
    font-size: 0.85rem;
    line-height: 1.6;
    outline: none;
    transition: border-color 0.2s, box-shadow 0.2s;
    width: 100%;
}

textarea {
    height: 80px;
    min-height: 80px;
    resize: vertical;
}

textarea:focus,
input[type='text']:focus {
    border-color: var(--color-primary);
    box-shadow: 0 0 0 3px rgba(37, 99, 235, 0.1);
}

/* ----- 按钮 ----- */
.btn-group {
    display: flex;
    gap: var(--space-sm);
    margin-top: 12px;
    flex-wrap: wrap;
    align-items: center;
}

.btn {
    display: inline-flex;
    align-items: center;
    gap: 5px;
    padding: 7px 16px;
    border-radius: var(--radius-sm);
    border: 1px solid var(--color-border);
    background: var(--color-surface);
    color: var(--text-primary);
    cursor: pointer;
    font-size: 0.83rem;
    font-weight: 500;
    font-family: var(--font-sans);
    transition: all 0.15s;
    white-space: nowrap;
    user-select: none;
}

.btn:hover {
    background: var(--color-surface-hover);
    border-color: #cbd5e1;
}

.btn:active {
    transform: scale(0.98);
}

.btn:disabled {
    opacity: 0.5;
    cursor: not-allowed;
    pointer-events: none;
}

.btn-primary {
    background: var(--color-primary);
    border-color: var(--color-primary);
    color: var(--text-inverse);
    font-weight: 600;
}

.btn-primary:hover {
    background: var(--color-primary-hover);
    border-color: var(--color-primary-hover);
}

/* ----- 六框翻译 ----- */
.orf-row {
    font-family: var(--font-mono);
    font-size: 0.82rem;
    padding: 9px 14px;
    margin: 2px 0;
    border-radius: var(--radius-sm);
    word-break: break-all;
    line-height: 1.9;
    display: flex;
    align-items: baseline;
    transition: background 0.15s;
    border: 1px solid transparent;
}

.orf-row:hover {
    background: var(--color-bg);
    border-color: var(--color-border);
}

.orf-row.forward-1 { background: #f0fdf4; }
.orf-row.forward-2 { background: #eff6ff; }
.orf-row.forward-3 { background: #f0fdf4; }
.orf-row.reverse-1 { background: #fef2f2; }
.orf-row.reverse-2 { background: #fff7ed; }
.orf-row.reverse-3 { background: #fef2f2; }

.orf-label {
    font-weight: 650;
    font-size: 0.72rem;
    color: var(--text-secondary);
    min-width: 90px;
    display: inline-block;
    letter-spacing: -0.2px;
    text-transform: uppercase;
    flex-shrink: 0;
}

/* 氨基酸标记 */
.aa-M {
    background: var(--color-success);
    color: #fff;
    font-weight: 700;
    padding: 1px 5px;
    border-radius: 3px;
    font-size: 0.9em;
}

.aa-stop {
    background: var(--color-error);
    color: #fff;
    font-weight: 700;
    padding: 1px 5px;
    border-radius: 3px;
    font-size: 0.9em;
}

/* 比对差异高亮 */
.diff-highlight {
    background: #fecaca;
    color: #991b1b;
    padding: 1px 4px;
    border-radius: 3px;
    font-weight: 600;
}

/* ----- 折叠/展开 ----- */
.orf-collapse-btn {
    background: none;
    border: none;
    color: var(--text-tertiary);
    cursor: pointer;
    font-size: 0.65rem;
    padding: 0 4px;
    margin-right: 4px;
    transition: color 0.15s;
    flex-shrink: 0;
    line-height: 1;
}

.orf-collapse-btn:hover {
    color: var(--color-primary);
}

.orf-preview {
    display: none;
    font-family: var(--font-mono);
    font-size: 0.82rem;
    color: var(--text-tertiary);
    word-break: break-all;
    line-height: 1.9;
}

.orf-row.collapsed .orf-seq-wrap { display: none; }
.orf-row.collapsed .orf-preview { display: inline; }

/* ----- 比对匹配闪烁动画 ----- */
@keyframes matchFlash {
    0%,
    100% {
        box-shadow: inset 0 0 0 rgba(37, 99, 235, 0);
        outline: 2px solid transparent;
    }
    25% {
        box-shadow: inset 0 0 40px rgba(37, 99, 235, 0.15);
        outline: 2px solid var(--color-primary);
    }
    50% {
        box-shadow: inset 0 0 80px rgba(37, 99, 235, 0.2);
        outline: 2px solid var(--color-primary);
    }
    75% {
        box-shadow: inset 0 0 40px rgba(37, 99, 235, 0.15);
        outline: 2px solid var(--color-primary);
    }
}

.orf-row.match-flash {
    animation: matchFlash 1s ease-in-out 5;
    position: relative;
    z-index: 2;
}

.orf-toggle-all {
    margin-left: auto;
    background: none;
    border: 1px solid var(--color-border);
    color: var(--text-secondary);
    cursor: pointer;
    font-size: 0.72rem;
    font-weight: 500;
    padding: 3px 10px;
    border-radius: var(--radius-sm);
    transition: all 0.15s;
    white-space: nowrap;
    font-family: var(--font-sans);
}

.orf-toggle-all:hover {
    background: var(--color-primary-light);
    border-color: var(--color-primary-border);
    color: var(--color-primary);
}

/* ----- 单选 ----- */
.orf-select-row {
    display: flex;
    align-items: center;
    padding: 4px 14px;
    margin-bottom: 8px;
}

.orf-radio-label {
    font-size: 0.82rem;
    color: var(--text-secondary);
    cursor: pointer;
    display: flex;
    align-items: center;
    gap: 6px;
    font-weight: 500;
}

.orf-radio {
    accent-color: var(--color-primary);
    cursor: pointer;
}

.orf-row .orf-radio {
    margin-right: 10px;
}

/* ----- 侧边栏比对 ----- */
.compare-input {
    width: 100%;
    height: 56px;
    min-height: 56px;
    font-family: var(--font-mono);
    background: var(--color-bg);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-md);
    padding: 10px 14px;
    color: var(--text-primary);
    resize: vertical;
    font-size: 0.82rem;
    outline: none;
    transition: border-color 0.2s, box-shadow 0.2s;
}

.compare-input:focus {
    border-color: var(--color-primary);
    box-shadow: 0 0 0 3px rgba(37, 99, 235, 0.1);
}

.result-box {
    background: var(--color-bg);
    border-radius: var(--radius-md);
    padding: 14px 16px;
    margin-top: 12px;
    border-left: 3px solid var(--color-primary);
    font-size: 0.85rem;
    line-height: 1.7;
    min-height: 80px;
}

.result-summary {
    font-weight: 650;
    color: var(--color-success);
    margin-bottom: 6px;
}

/* ----- 统计数字 ----- */
.guide-stats {
    display: flex;
    justify-content: space-between;
    gap: 10px;
}

.guide-stat-item {
    background: var(--color-bg);
    border-radius: var(--radius-md);
    padding: 12px 14px;
    text-align: center;
    flex: 1;
}

.guide-stat-num {
    display: block;
    font-family: var(--font-mono);
    font-size: 1.35rem;
    font-weight: 700;
    color: var(--color-primary);
}

.guide-stat-label {
    display: block;
    font-size: 0.7rem;
    color: var(--text-tertiary);
    margin-top: 2px;
    text-transform: uppercase;
    letter-spacing: 0.3px;
}

/* ----- 状态栏 ----- */
.statusbar {
    background: var(--color-surface);
    border-top: 1px solid var(--color-border);
    padding: 9px var(--space-lg);
    font-size: 0.78rem;
    color: var(--text-secondary);
    display: flex;
    justify-content: space-between;
    font-weight: 500;
}

/* ----- 模态框 ----- */
.modal-overlay {
    display: none;
    position: fixed;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
    background: rgba(15, 23, 42, 0.5);
    backdrop-filter: blur(4px);
    z-index: 2000;
    justify-content: center;
    align-items: center;
}

.modal-overlay.show {
    display: flex;
}

.modal-panel {
    background: var(--color-surface);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-lg);
    width: 92%;
    max-width: 680px;
    max-height: 82vh;
    overflow-y: auto;
    box-shadow: var(--shadow-lg);
    padding: 24px 28px;
}

.modal-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: 20px;
    padding-bottom: 14px;
    border-bottom: 1px solid var(--color-border-light);
}

.modal-title {
    font-size: 1.1rem;
    font-weight: 650;
    color: var(--text-primary);
}

.modal-close {
    background: none;
    border: none;
    color: var(--text-tertiary);
    font-size: 1.3rem;
    cursor: pointer;
    transition: color 0.15s;
    padding: 4px 8px;
    border-radius: var(--radius-sm);
    line-height: 1;
}

.modal-close:hover {
    color: var(--text-primary);
    background: var(--color-bg);
}

.modal-body {
    color: var(--text-primary);
}

/* ----- 示例卡片 ----- */
.example-list {
    display: grid;
    grid-template-columns: repeat(auto-fill, minmax(240px, 1fr));
    gap: 10px;
}

.example-card {
    background: var(--color-bg);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-md);
    padding: 14px 16px;
    cursor: pointer;
    transition: all 0.15s;
}

.example-card:hover {
    border-color: var(--color-primary-border);
    background: var(--color-primary-light);
}

.example-card-title {
    font-weight: 650;
    font-size: 0.9rem;
    color: var(--text-primary);
    margin-bottom: 4px;
}

.example-card-desc {
    font-size: 0.78rem;
    color: var(--text-tertiary);
    line-height: 1.5;
}

/* ----- 在线基因芯片 ----- */
.remote-gene-grid {
    display: grid;
    grid-template-columns: repeat(auto-fill, minmax(150px, 1fr));
    gap: 8px;
}

.remote-gene-chip {
    background: var(--color-bg);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-sm);
    padding: 10px 12px;
    cursor: pointer;
    transition: all 0.15s;
    text-align: center;
    font-size: 0.8rem;
    color: var(--text-primary);
}

.remote-gene-chip:hover {
    border-color: var(--color-primary-border);
    background: var(--color-primary-light);
    color: var(--color-primary);
}

.remote-gene-chip .chip-symbol {
    font-weight: 700;
    font-size: 0.95rem;
}

.remote-gene-chip .chip-desc {
    font-size: 0.68rem;
    color: var(--text-tertiary);
    margin-top: 2px;
}

/* ----- 下拉菜单 ----- */
.dropdown-wrapper {
    position: relative;
    display: inline-block;
}

.dropdown-menu {
    display: none;
    position: absolute;
    top: calc(100% + 6px);
    left: 0;
    background: var(--color-surface);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-md);
    min-width: 300px;
    z-index: 1000;
    padding: 4px 0;
    box-shadow: var(--shadow-lg);
}

.dropdown-menu.show {
    display: block;
}

.dropdown-item {
    padding: 10px 16px;
    font-size: 0.83rem;
    color: var(--text-primary);
    cursor: pointer;
    transition: background 0.1s;
    border-bottom: 1px solid var(--color-border-light);
}

.dropdown-item:last-child {
    border-bottom: none;
}

.dropdown-item:hover {
    background: var(--color-primary-light);
}

.dropdown-item .item-title {
    font-weight: 600;
}

.dropdown-item .item-desc {
    font-size: 0.73rem;
    color: var(--text-tertiary);
    margin-top: 2px;
}

/* 输入卡片层级 */
.card-input {
    position: relative;
    z-index: 20;
    overflow: visible;
}

.main-panel .card:last-child {
    position: relative;
    z-index: 1;
}

/* ----- 历史记录 ----- */
.history-list {
    display: flex;
    flex-direction: column;
    gap: 8px;
}

.history-item {
    background: var(--color-bg);
    border: 1px solid var(--color-border);
    border-radius: var(--radius-md);
    padding: 12px 16px;
    display: flex;
    justify-content: space-between;
    align-items: center;
    transition: all 0.15s;
}

.history-item:hover {
    border-color: var(--color-primary-border);
}

.history-info {
    flex: 1;
    min-width: 0;
}

.history-source {
    font-weight: 600;
    font-size: 0.87rem;
    color: var(--text-primary);
    margin-bottom: 4px;
}

.history-meta {
    font-size: 0.73rem;
    color: var(--text-tertiary);
    display: flex;
    gap: 12px;
    flex-wrap: wrap;
}

.history-actions {
    display: flex;
    gap: 6px;
    flex-shrink: 0;
    margin-left: 12px;
}

.history-actions .btn {
    padding: 4px 10px;
    font-size: 0.75rem;
}

/* ----- 帮助内容 ----- */
.help-content h3 {
    font-size: 0.95rem;
    color: var(--text-primary);
    margin-top: 20px;
    margin-bottom: 10px;
    font-weight: 650;
}

.help-content ol,
.help-content ul {
    padding-left: 20px;
    line-height: 1.8;
    font-size: 0.87rem;
}

.help-content li {
    margin-bottom: 6px;
}

/* ----- 比对结果 ----- */
.result-box div {
    word-break: break-all;
    overflow-wrap: break-word;
    max-width: 100%;
    font-size: 0.88rem;
}

/* ----- 加载动画 ----- */
@keyframes spin {
    0% { transform: rotate(0deg); }
    100% { transform: rotate(360deg); }
}

.spinner {
    display: inline-block;
    width: 14px;
    height: 14px;
    border: 2px solid var(--color-border);
    border-top-color: var(--color-primary);
    border-radius: 50%;
    animation: spin 0.6s linear infinite;
    margin-right: 5px;
    vertical-align: middle;
}